Chromophobe renal cell carcinoma
MONDO:0017885Chromophobe renal cell carcinoma is a rare subtype of renal cell carcinoma, originating from the intercalating cells of the collecting ducts and macroscopically manifesting as a well-circumscribed, highly lobulated, solid tumor that is usually diagnosed at an early stage. It is frequently asymptomatic, or may present with nonspecific symptoms, such as weight loss, fever or fatigue. The classic presentation observed in renal tumors (hematuria, flank pain and palpable mass) is occasionally observed and usually indicates an advanced stage of the disease. It is most frequently sporadic however, several familial cases, associated with Birt-Hogg DubC) syndrome, have been described.
Also known as: chromophobe adenocarcinoma, chromophobe carcinoma, chromophobe carcinoma of kidney, chromophobe carcinoma of the kidney, chromophobe cell carcinoma of kidney, chromophobe cell carcinoma of the kidney, chromophobe renal cell adenocarcinoma, chromophobe renal cell cancer
2789 clinical trials for this condition and its sub-types, 13 tagged with Chromophobe renal cell carcinoma itself.
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Browse by category →Sub-types of Chromophobe renal cell carcinoma
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New hope for rare cancers: Triple-Drug attack shows promise
Disease control Recruiting nowThis phase II trial is testing whether a combination of three drugs—cabozantinib, nivolumab, and ipilimumab—can shrink or slow the growth of rare genitourinary cancers that have spread. About 314 adults with these uncommon tumors will receive the drugs. The goal is to see if the …
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 21, 2026 22:00 UTC
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New smart drug targets tough cancers in early human test
Disease control Recruiting nowThis early-stage trial tests a new drug called NN3201 in people with advanced cancers that have a specific marker called c-Kit. The drug is designed to deliver a chemotherapy agent directly to cancer cells, potentially killing them while sparing healthy tissue. The study will enr…
Phase 1 • Sponsor: Novelty Nobility, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Scientists track families to unlock secrets of inherited kidney cancer
Knowledge-focused Recruiting nowThis study follows families with a history of inherited kidney cancer to learn more about the disease's genetic causes and how it progresses. Researchers will collect blood, tissue, and urine samples from affected individuals and their relatives. The goal is to identify new genes…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Scientists track Cancer's diet in real time during surgery
Knowledge-focused Recruiting nowThis study looks at how kidney and bladder cancers use nutrients like sugar and fat to grow. Participants receive a harmless nutrient tracer during surgery or biopsy, and researchers collect blood and tissue samples to analyze cancer metabolism. The study does not change standard…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC