Charcot-Marie-Tooth disease type 1
MONDO:0019011Charcot-Marie-Tooth disease type 1 (CMT1) is a group of autosomal dominant demyelinating peripheral neuropathies characterized by distal weakness and atrophy, sensory loss, foot deformities, and slow nerve conduction velocity.
Also known as: CMT1, Charcot-Marie-Tooth neuropathy type 1, autosomal dominant demyelinating Charcot-Marie-Tooth disease, hereditary motor and sensory neuropathy type 1, Charcot-Marie-Tooth type 1
46 clinical trials for this condition and its sub-types, 4 tagged with Charcot-Marie-Tooth disease type 1 itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Charcot-Marie-Tooth disease type 1
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Charcot-Marie-Tooth disease type 1F 21 trials
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Charcot-Marie-Tooth disease type 1A 16 trials
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Charcot-Marie-Tooth disease type 1B 3 trials
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Experimental stem cells tested for rare nerve disease
Disease control CompletedThis completed early trial tested a single intravenous dose of EN001 stem cells in 3 adults with Charcot-Marie-Tooth disease type 1E, a severe hereditary nerve disorder with no approved treatment. The main goal was to check safety, including infusion reactions, while also looking…
Sponsor: Samsung Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New drug shows promise for nerve disease that affects walking
Symptom relief CompletedThis study tested a new medicine called NMD670 in 81 adults with Charcot-Marie-Tooth disease types 1 and 2. Participants took either the drug or a placebo twice daily for 21 days. The main goal was to see if the drug could improve walking distance in 6 minutes. The study also che…
Phase 2 • Sponsor: NMD Pharma A/S • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC