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Castleman-Kojima disease

MONDO:0018702

A clinicopathologic variant of multicentric Castleman's disease characterized by thrombocytopenia, ascites (anasarca), microcytic anemia, myelofibrosis, renal dysfunction, and organomegaly

Also known as: TAFRO syndrome, thrombocytopenia-anasarca-fever-renal insufficiency-organomegaly syndrome

83 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Autoimmune disease (283) Hereditary disease (172) Immune system disorder (140) Inborn error of immunity (113) Lymphoproliferative syndrome (68) Hypersensitivity reaction disease (29) Syndromic disease (24) Human disease (14) Autoimmune lymphoproliferative syndrome (11)

Trials to join now! 38 Not yet recruiting 11 Not yet finished but already full! 12 Completed 21 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Terminated

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC