Calcinosis
MONDO:0002123Deposition of calcium in the tissues. It may be the result of a metabolic disorder or long-standing infection, or it may be associated with the presence of cancer.
Also known as: calcification, calcium deposit(s), deposit(s), calcium, macrocalcification, pathologic calcification, pathologically calcified structure
47 clinical trials for this condition and its sub-types, 30 tagged with Calcinosis itself.
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Sub-types of Calcinosis
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Calciphylaxis 9 trials
2 sub-types
- Calciphylaxis cutis 0 trials
- Visceral calciphylaxis 0 trials
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Nephrocalcinosis 7 trials · 8 incl. sub-types
1 sub-type
- Renal hypomagnesemia 3 1 trial
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Familial tumoral calcinosis 1 trial
5 sub-types
- Familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome 0 trials
- Normophosphatemic familial tumoral calcinosis 0 trials
- Tumoral calcinosis, hyperphosphatemic, familial, 1 0 trials
- Tumoral calcinosis, hyperphosphatemic, familial, 2 0 trials
- Tumoral calcinosis, hyperphosphatemic, familial, 3 0 trials
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Sound waves to zap artery calcium before stenting: new trial launches
Disease control Recruiting nowThis study tests a new device that uses sound waves (lithotripsy) to break up hard calcium deposits in the carotid arteries of the neck before placing a stent. About 185 people with heavily calcified carotid arteries will be enrolled. The main goal is to see if the procedure is s…
Sponsor: Shockwave Medical, Inc. • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Shockwave therapy may improve stent success in hardened leg arteries
Disease control Recruiting nowThis study tests whether using a special shockwave device to break up calcium before placing a stent works better than the usual balloon angioplasty in people with peripheral artery disease (PAD) and heavily calcified leg arteries. About 120 participants will be randomly assigned…
Sponsor: University of Leipzig • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could a simple injection melt away painful calcium deposits?
Symptom relief Recruiting nowThis study tests whether injecting sodium thiosulfate directly into painful calcium deposits (calcinosis) can shrink them and ease symptoms. Twenty adults with scleroderma, dermatomyositis, or mixed connective tissue disease will receive ultrasound-guided injections. The main goa…
Phase 2 • Sponsor: Robyn T. Domsic, MD, MPH • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Leftover surgery tissue could unlock secrets of hardening arteries and bones
Knowledge-focused Recruiting nowThis study uses leftover tissue from heart and orthopedic surgeries to learn more about how calcification (hardening) happens in bones and blood vessels. Researchers will grow cells from these tissues in the lab to study the process. The goal is to better understand the disease, …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New imaging tool could better track painful calcium buildup in scleroderma
Knowledge-focused Recruiting nowThis study aims to develop a better way to measure calcium deposits under the skin in people with scleroderma. Researchers will use CT scans and special software to see if these measurements match how patients report their symptoms. About 56 adults with scleroderma and calcium de…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Does calcium slow stent healing? new study investigates
Knowledge-focused Recruiting nowThis study looks at how calcium deposits in artery walls affect the healing of a stent (a small mesh tube) placed to open blocked arteries. Researchers will use a special camera to compare stent healing over calcium spots versus healthy tissue in 40 patients with coronary artery …
Sponsor: Fundación EPIC • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC