Brain glioma
MONDO:0005499A malignant glioma that involves the brain.
Also known as: brain malignant glioma, malignant glioma of brain
3083 clinical trials for this condition and its sub-types, 29 tagged with Brain glioma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Brain glioma
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Brain stem glioma 11 trials · 101 incl. sub-types
5 sub-types
- Childhood brain stem glioma 0 trials · 95 incl. sub-types Sub-types →
- Adult brainstem glioma 1 trial Sub-types →
- Brain stem glioblastoma 1 trial
- Brain stem astrocytic neoplasm 0 trials Sub-types →
- Brain stem ependymoma 0 trials
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Brain glioblastoma 24 trials · 87 incl. sub-types
3 sub-types
- Gliosarcoma 65 trials
- Giant cell glioblastoma 7 trials
- Brain stem glioblastoma 1 trial
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Ependymal tumor of brain 3 trials · 5 incl. sub-types
6 sub-types
- Adult brain ependymoma 1 trial
- Infratentorial ependymal tumor 1 trial Sub-types →
- Brain stem ependymoma 0 trials
- Frontal lobe ependymal tumor 0 trials
- Parietal lobe ependymal tumor 0 trials
- Supratentorial ependymal tumor 0 trials Sub-types →
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Gliomatosis cerebri 1 trial
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Diencephalic astrocytomas 0 trials · 1 incl. sub-types
3 sub-types
- Pineal gland astrocytoma 1 trial
- Optic tract astrocytoma 0 trials Sub-types →
- Pituicytoma 0 trials
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Brain oligodendroglioma 0 trials
1 sub-type
- Corpus callosum oligodendroglioma 0 trials
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Childhood cerebral astrocytoma 0 trials
1 sub-type
- Childhood optic tract astrocytoma 0 trials
Most studied deeper sub-types
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Could a dementia drug shield kids' brains from radiation damage?
Disease control CompletedThis pilot study tested whether memantine, a drug used for dementia in adults, could help prevent memory and thinking problems in children receiving brain radiation for tumors like glioma or craniopharyngioma. 41 children aged 6-21 took either memantine or a placebo during radiat…
Phase 2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug targets tough childhood cancers with genetic flaws
Disease control CompletedThis phase 2 trial tested the drug samotolisib in 18 children and young adults with advanced solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that had spread, returned, or stopped responding to treatment. Only patients whose tumors had specific mutations in the TSC or…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Glow-in-the-Dark drug could help brain cancer surgery
Disease control CompletedThis completed Phase III trial tested a drug called 5-aminolevulinic acid (5-ALA) in 86 adults with malignant brain glioma. Patients took the drug orally before surgery, causing tumor cells to glow under a special light. This helps surgeons see and remove more cancerous tissue. T…
Phase 3 • Sponsor: Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New contrast agent shows promise for brain tumor MRI scans
Diagnosis CompletedThis completed Phase 3 trial tested whether Elucirem (gadopiclenol) provides better MRI images of brain gliomas compared to the standard contrast agent Dotarem. 138 adults with primary or recurrent brain tumors received one of the two agents during DSC-MRI perfusion scans. The ma…
Phase 3 • Sponsor: Guerbet • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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Can a Tumor's genetic blueprint guide better treatment for kids with brain cancer?
Knowledge-focused CompletedThis pilot trial explores whether using a tumor's molecular profile—its gene expression and DNA sequencing—can help doctors choose a personalized treatment plan for children and young adults with high-grade glioma (a type of brain cancer). Participants receive a recommendation fr…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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New imaging method could reduce need for brain tumor biopsies
Knowledge-focused CompletedThis completed study looked at whether a special PET scan technique called radiomics can help doctors figure out the type and behavior of brain tumors (gliomas) without needing a surgical biopsy. Researchers analyzed scans from 1000 patients who had already received an 18F-FDOPA …
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC