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Bleeding diathesis due to thromboxane synthesis deficiency

MONDO:0800446

A rare, genetic, isolated constitutional thrombocytopenia disease characterized by impaired platelet aggregation resulting from a defect in thromboxane synthesis or signaling, manifesting with mild to moderate mucocutaneous, gastrointestinal or surgical bleeding (e.g. easy bruising, prolonged epistaxis, excessive bleeding after a tooth extraction).

44 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Hereditary disease (172) Hematologic disorder (160) Hemorrhagic disease (100) Blood platelet disease (15) Human disease (14) Inherited bleeding disorder, platelet-type (6) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0)
Trials to join now! 22 Not yet recruiting 2 Not yet finished but already full! 4 Completed 15 Terminated 1
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  • Can extra care after transplant help older patients live better?

    Disease control Terminated

    This study tested two extra care programs—supportive palliative care and clinical management of other health issues—for older or frail patients who had a donor stem cell transplant. The goal was to see if these programs could improve quality of life and survival compared to stand…

    Phase: PHASE2, PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control

    Last updated Jun 27, 2026 08:10 UTC

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