Bile duct disorder
MONDO:0002887A disease involving the bile duct.
Also known as: bile duct disease, bile duct disease or disorder, bile duct disorder, disease of bile duct, disease or disorder of bile duct, disorder of bile duct
729 clinical trials for this condition and its sub-types, 16 tagged with Bile duct disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Bile duct disorder
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Bile duct neoplasm 41 trials · 469 incl. sub-types
4 sub-types
- Bile duct cancer 34 trials · 468 incl. sub-types Sub-types →
- Extrahepatic bile duct neoplasm 0 trials · 431 incl. sub-types Sub-types →
- Bile duct adenoma 0 trials Sub-types →
- Bile duct papillary neoplasm 0 trials Sub-types →
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Non-neoplastic bile duct disorder 0 trials · 172 incl. sub-types
5 sub-types
- Cholangitis 17 trials · 139 incl. sub-types Sub-types →
- Biliary atresia 24 trials Sub-types →
- Obstructive jaundice 11 trials
- Caroli disease 1 trial
- Extrahepatic cholestasis 0 trials Sub-types →
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Common bile duct disorder 0 trials · 120 incl. sub-types
3 sub-types
- Common bile duct neoplasm 2 trials · 71 incl. sub-types Sub-types →
- Choledocholithiasis 40 trials
- Biliary dyskinesia 12 trials
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Cholestasis 44 trials · 91 incl. sub-types
5 sub-types
- Biliary atresia 24 trials Sub-types →
- Intrahepatic cholestasis 3 trials · 24 incl. sub-types Sub-types →
- Obstructive jaundice 11 trials
- Parenteral nutrition-associated cholestasis 5 trials
- Extrahepatic cholestasis 0 trials Sub-types →
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Bile duct cyst 10 trials
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Perforation of bile duct 1 trial
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Fibrosis of bile duct 0 trials
Most studied deeper sub-types
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Hope for rare liver disease: drug aims to ease severe itching in children
Disease control CompletedThis study tests the long-term safety of maralixibat, an oral medication, in children with progressive familial intrahepatic cholestasis (PFIC), a rare liver disease that causes intense itching. Participants who completed a prior study will receive maralixibat twice daily. Resear…
Phase 3 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug shows promise for babies with rare liver disorders
Disease control CompletedThis study tested the safety of a drug called maralixibat in 27 infants under 12 months old with Alagille syndrome or progressive familial intrahepatic cholestasis (PFIC), two rare liver diseases that cause bile buildup. The drug is given as an oral solution and aims to reduce bi…
Phase 2 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Liver drug maralixibat tested for Long-Term safety in rare disease patients
Disease control CompletedThis study looked at the long-term safety of a drug called maralixibat in 52 people with cholestatic liver disease, including Alagille Syndrome and other rare conditions. Participants had already taken maralixibat in an earlier study. Researchers tracked side effects and how well…
Phase 2 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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New imaging tool aims to sharpen bile duct diagnosis
Diagnosis CompletedThis completed study tested a device called NvisionVLE® that helps doctors see bile duct details during a procedure called ERCP. Only 3 adults who had the procedure between 2017 and 2019 took part. The goal was to check if the device is safe and can better find abnormalities to g…
Sponsor: Methodist Health System • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Extra fluids during ERCP may prevent pancreatitis, study finds
Prevention CompletedThis study looked at whether giving more IV fluids (aggressive hydration) during an ERCP procedure can prevent pancreatitis, a common complication. 126 adults having their first ERCP were randomly assigned to receive either standard or extra fluids. The goal was to see if extra f…
Sponsor: Lahore General Hospital • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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New surgical clip tool tested in 161 patients
Knowledge-focused CompletedThis study looked at a new device called AE05ML that helps surgeons place clips on blood vessels and other tissues during keyhole surgery. The goal was to see if the device is safe and works well. A total of 161 adults took part in the study.
Sponsor: Teleflex • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC