Autoimmune interstitial lung disease-arthritis syndrome
MONDO:0014629A respiratory disease characterized by interstitial lung disease (often with pulmonary hemorrhage) and inflammatory arthritis, associated with high-titer autoantibodies (including anti-nuclear and anti-neutrophil cytoplasmic antibodies, and rheumatoid factor). Patients present from infancy to adolescence with tachypnea, cough, hemoptysis, and/or joint pain. Some patients may also develop glomerular disease.
Also known as: COPA Syndrome, autoinflammation and autoimmunity, systemic, with immune dysregulation, AILJK, autoimmune interstitial lung, joint, and kidney disease
49 clinical trials for this condition and its sub-types.
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Pausing arthritis drug may boost pneumonia Shot's power
Disease control Not yet recruitingThis study tests whether temporarily stopping methotrexate for 2 weeks after receiving a pneumonia vaccine (PCV20) helps the vaccine work better in adults with autoimmune rheumatic diseases like rheumatoid arthritis or lupus. About 192 participants with stable, low disease activi…
Phase: PHASE4 • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Cartoons and stories soothe Kids' fear during breathing treatments
Symptom relief Not yet recruitingThis study looks at whether watching cartoons or listening to breath-synchronized interactive stories can help children aged 6-9 feel less afraid and more comfortable while using a nebulizer for breathing medication. About 96 children with respiratory conditions will be randomly …
Phase: NA • Sponsor: Mersin University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Cold therapy could take the ouch out of blood tests
Symptom relief Not yet recruitingThis study tests if applying cold (cryotherapy) to the wrist before a blood draw from the artery can reduce pain. It involves 258 adults with chronic respiratory diseases who need this test. The goal is to find a simple, drug-free way to make the procedure less painful.
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Can a quick skin scan reveal hidden inflammation in arthritis?
Knowledge-focused Not yet recruitingThis study will measure harmful molecules called AGEs in 300 people with various rheumatic diseases (like rheumatoid arthritis and ankylosing spondylitis) and compare them to healthy volunteers. AGEs build up over time and can cause inflammation. Researchers will use a non-invasi…
Sponsor: Bursa City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New blood tests aim to unlock mysteries of rare inflammatory diseases
Knowledge-focused Not yet recruitingThis study aims to better understand rare autoinflammatory diseases by developing blood tests that measure inflammation markers. Researchers will analyze blood samples from 60 adults and children with these conditions. The goal is to identify specific inflammation pathways, which…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:44 UTC