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Autoimmune enteropathy

MONDO:0019787

Severe-immune mediated enteropathy describes a variety of intestinal disorders that can range from a serious, early-onset systemic disease (IPEX) to a mild isolated gastrointestinal disease. In children it manifests with severe diarrhea and dehydration in the presence of characteristic antibodies (anti-enterocyte and anti-goblet cell) and in adults with chronic diarrhea, malabsorption and weight loss.

Also known as: immune-mediated protracted diarrhea of infancy, immune-mediated protracted diarrhoea of infancy, severe immune-mediated enteropathy

50 clinical trials for this condition and its sub-types.

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Sub-types

Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (9) Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome (0) Autoimmune enteropathy type 3 (0) Primary autoimmune enteropathy (0)

Broader categories

Disease (618) Autoimmune disease (283) Digestive system disorder (141) Immune system disorder (140) Intestinal disorder (55) Human disease (14) Malabsorption syndrome (10) Autoimmune disorder of gastrointestinal tract (0) Disease by body system or component (0)

Trials to join now! 23 Not yet recruiting 5 Not yet finished but already full! 9 Completed 12 Terminated 1

Biopsy tolerance study ends early – what we know

Knowledge-focused Terminated

This study aimed to understand how well patients tolerate biopsies for autoimmune diseases and whether they feel properly informed. It planned to enroll 505 people but was terminated early. The results may help improve patient experience with these common procedures.

Sponsor: University Hospital, Brest • Aim: Knowledge-focused

Last updated Jun 28, 2026 00:00 UTC

Autoimmune enteropathy

Sub-types

Broader categories

Biopsy tolerance study ends early – what we know