Atypical endometrial hyperplasia
MONDO:0006096An endometrial hyperplasia characterized by cytologic and architectural changes which may lead to endometrial carcinoma. Despite the atypical features and possible course, there is debate on whether to consider this a neoplasm. The relationship with endometrial intraepithelial neoplasia is also unclear.
Also known as: atypical hyperplasia of endometrium, atypical hyperplasia of the endometrium, endometrial hyperplasia with atypia
32 clinical trials for this condition and its sub-types.
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New combo therapy shows promise for uterine condition in obese women
Disease control CompletedThis study tested whether adding a diabetes drug (polyethylene glycol loxenatide) to a hormone-releasing IUD (LNG-IUS) helps women with a precancerous uterine condition called endometrial atypical hyperplasia. The 30 participants were all obese and wanted to preserve their fertil…
Phase: PHASE2, PHASE3 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Surgeons test safer way to remove oversized uteri without large cuts
Disease control CompletedThis study tested a new surgical method to remove very large uteri (over 20 weeks size) during total laparoscopic hysterectomy. The technique uses a cold knife to cut the uterus into a long strip that can be pulled out through the vagina, avoiding large abdominal incisions. Twent…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Robot-Assisted hysterectomy shows promise in small trial
Symptom relief CompletedThis study tested the safety and effectiveness of the DEXTER robotic system in 52 patients having a hysterectomy (removal of the uterus) and related surgery for non-cancerous conditions. The main goals were to see if the robotic procedure could be completed without switching to o…
Sponsor: Distalmotion SA • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New stitch tool tested in robot surgeries shows promise
Knowledge-focused CompletedThis study tested a special stitch device (STRATAFIX Spiral PDS Plus) used in robot-assisted surgeries for weight loss (sleeve gastrectomy) and hysterectomy. 161 adults took part. The main goal was to see how well it controlled bleeding after stitching. Doctors also rated how eas…
Sponsor: Ethicon, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Robots vs. surgeons: which is better for hysterectomy?
Knowledge-focused CompletedThis study compared robot-assisted laparoscopy using the Senhance Surgical System to conventional laparoscopy for hysterectomy and other uterine surgeries. Researchers measured operating time, blood loss, and safety in 78 patients. The goal was to see if the robot offers advantag…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New surgical order may keep vagina longer after hysterectomy
Knowledge-focused CompletedThis study tested whether starting a hysterectomy by cutting the back of the vagina (posterior colpotomy first) helps keep the vagina longer compared to the usual method. Eighty women having a hysterectomy for non-cancer reasons took part. The main goal was to measure any differe…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC