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Age-related clonal hematopoiesis

MONDO:0100544

A precancerous condition characterized by the gradual, clonal expansion of hematopoietic stem and progenitor cells carrying specific, disruptive, and recurrent genetic variants, in individuals without clear diagnosis of hematological malignancies. It is associated with an increased risk of developing hematologic cancers.

Also known as: ARCH

46 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Hematologic disorder (160) Precancerous condition (50) Human disease (14) Clonal hematopoiesis (8) Premalignant hematological system disease (3) Cancer or benign tumor (0) Disease by body system or component (0) Disease by etiologic mechanism (0)
Trials to join now! 23 Not yet recruiting 2 Not yet finished but already full! 8 Completed 12 Terminated 1
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  • Can extra care after transplant help older patients live better?

    Disease control Terminated

    This study tested two extra care programs—supportive palliative care and clinical management of other health issues—for older or frail patients who had a donor stem cell transplant. The goal was to see if these programs could improve quality of life and survival compared to stand…

    Phase: PHASE2, PHASE3 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control

    Last updated Jun 27, 2026 08:10 UTC

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