Adult pure red cell aplasia

Adult pure red cell aplasia is a rare acquired aplastic anemia characterized by a severe normocytic anemia with normal peripheral leukocyte and platelet counts, reticulocytopenia, high serum ferritin and transferrin saturation levels and isolated, almost complete absence of erythroblasts in the bone marrow with normal granulopoesis and megakaryopoesis. It presents with signs of severe anemia (fatigue, lethargy, pallor, intolerance of physical exercise and exertional dyspnea) in the absence of hemorrhagic symptoms.

Also known as: adult pure red-cell aplasia, pure red-cell aplasia of adults, acquired PRCA, acquired pure red cell aplasia, idiopathic pure red cell aplasia

42 clinical trials for this condition and its sub-types.