Adenoid cystic carcinoma
MONDO:0004971A malignant tumor arising from the epithelial cells. Microscopically, the neoplastic epithelial cells form cylindrical spatial configurations (cribriform or classic type of adenoid cystic carcinoma), cordlike structures (tubular type of adenoid cystic carcinoma), or solid structures (basaloid variant of adenoid cystic carcinoma). Adenoid cystic carcinomas mostly occur in the salivary glands. Other primary sites of involvement include the lacrimal gland, the larynx, and the lungs. Adenoid cystic carcinomas spread along nerve sheaths, resulting in severe pain, and they tend to recur. Lymph node metastases are unusual; hematogenous tumor spread is characteristic.
Also known as: adenocystic carcinoma, adenoid cystic cancer, adenoid cystic carcinoma, cylindroid adenocarcinoma, cribriform carcinoma, cylindroma
2792 clinical trials for this condition and its sub-types, 47 tagged with Adenoid cystic carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Adenoid cystic carcinoma
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2 sub-types
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2 sub-types
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Adenoid cystic breast carcinoma 0 trials
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Cervical adenoid cystic carcinoma 0 trials
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Cutaneous adenocystic carcinoma 0 trials
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Esophageal adenoid cystic carcinoma 0 trials
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Laryngeal adenoid cystic carcinoma 0 trials
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Lung adenoid cystic carcinoma 0 trials
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Lymph node adenoid cystic carcinoma 0 trials
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Pharyngeal adenoid cystic carcinoma 0 trials
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Prostate adenoid cystic carcinoma 0 trials
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Tracheal adenoid cystic carcinoma 0 trials
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Vaginal adenoid cystic carcinoma 0 trials
Most studied deeper sub-types
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Can a targeted drug shrink rare salivary gland tumors?
Disease control Stopped earlyThis phase 2 trial is testing the drug rivoceranib in adults with recurrent or metastatic adenoid cystic carcinoma, a rare cancer that often starts in the salivary glands. The study aims to see if the drug can shrink tumors or slow the disease. Participants take rivoceranib table…
Phase 2 • Sponsor: Elevar Therapeutics • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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New cancer drug trial halted early – what we know
Disease control Stopped earlyThis study tested a new drug, felmetatug vedotin, alone or with pembrolizumab, in people with advanced solid tumors like ovarian, breast, and lung cancer. The goal was to check safety and find the right dose. The trial was terminated early, so results are limited.
Phase 1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Promising cancer imaging study halted after just one volunteer
Knowledge-focused Stopped earlyThis study aimed to see if a radioactive tracer could measure radiation doses in tumors and organs for people with recurrent or metastatic adenoid cystic carcinoma that cannot be surgically removed. Only one participant was enrolled before the study was terminated. The main goal …
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC