Acquired hemophilia A
MONDO:0035735An acquired form of hemophilia A, resulting in spontaneous bleeding in individuals with no history of bleeding disorders. It is believed to be caused by spontaneous inhibition of clotting factor VIII by autoantibodies, and is usually associated with other autoimmune conditions.
Also known as: AHA
16 clinical trials for this condition and its sub-types.
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Battlefield plasma goes civil: can a powder save trauma victims?
Disease control CompletedThis study tested a freeze-dried plasma product that can be mixed with water in 6 minutes, avoiding the long thaw time of standard plasma. It included 42 trauma patients with severe bleeding who needed blood transfusions. The goal was to see if faster plasma delivery could improv…
Phase: PHASE3 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New hope for rare bleeding disorder: Single-Dose rituximab may replace daily chemo
Disease control CompletedThis study tested two treatments for acquired hemophilia A, a rare condition where the immune system attacks clotting factor VIII. 66 adults received either steroid plus a single dose of rituximab or steroid plus daily cyclophosphamide. The goal was to see which combination clear…
Phase: PHASE4 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New blood product could cut transfusions in major surgeries
Disease control CompletedThis study tested a pathogen-reduced version of cryoprecipitate, a blood product that helps blood clot, in 208 patients undergoing liver transplant or heart surgery. The goal was to see if having this product readily available could stop bleeding early and reduce the need for oth…
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC