Acanthosis nigricans

MONDO:0007035

A melanotic cutaneous lesion that develops in the axilla and other body folds. It may be idiopathic, drug-induced, or it may be associated with the presence of an endocrine disorder or malignancy.

Also known as: acanthosis nigricans, acanthosis nigricans (disease), an - acanthosis nigricans

5 clinical trials for this condition and its sub-types, 4 tagged with Acanthosis nigricans itself.

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Where it sits in the disease tree

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↑ Dermatitis (1625)

Sub-types of Acanthosis nigricans

Acanthosis nigricans-insulin resistance-muscle cramps-acral enlargement syndrome 0 trials
Familial acanthosis nigricans 0 trials

Including sub-types (5) Tagged with Acanthosis nigricans (4)

Not yet recruiting 1 Completed 3

Can a laser and diabetes drug erase dark skin patches?

Disease control Not yet recruiting

This trial tests whether combining fractional carbon dioxide laser treatment with a topical metformin cream works better than laser alone for acanthosis nigricans—dark, velvety patches on the neck. About 34 adults with this condition will have one side of their neck treated with …

Phase 1 • Sponsor: Al-Azhar University • Aim: Disease control

Last updated Aug 14, 2026 00:00 UTC

Acanthosis nigricans

Where it sits in the disease tree

Can a laser and diabetes drug erase dark skin patches?