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127005 trials found · Page 6169 of 6351
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Which feeding strategy works best for ventilator patients?
Knowledge-focused CompletedThe aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Kidney donation may raise risk of scrotal surgery later in life
Knowledge-focused CompletedThis study will examine whether laparoscopic nephrectomy is associated with a higher long-term risk of receiving scrotal surgery in male living kidney donors compared to male nondonors from the general population who have similar baseline health indicators. Both groups will be fo…
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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96,000 adventists help uncover Diet-Cancer links
Knowledge-focused OngoingThe Adventist Health Study-2 is a long-term study, exploring the links between lifestyle, diet, and disease outcomes among Seventh-day Adventists. More than 96,000 church members from the U.S. and Canada are participating in the current study, AHS-2, conducted by researchers at t…
Sponsor: Loma Linda University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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NIH launches major lyme disease observation study to uncover hidden clues
Knowledge-focused Recruiting nowThis study is designed to establish a population of patients with Lyme disease for evaluation, treatment and follow-up to learn more about the infection. Patients with active Lyme disease may be eligible for this study. Participants will have a medical history and physical exam…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Radiation study seeks samples, not a cure
Knowledge-focused By invitation onlyBackground: -Research in NCI's Radiation Oncology Branch depends on the availability of blood and urine samples from patients receiving radiation therapy. Objectives: -To explore the effects of radiation therapy on gene expression in white blood cells, to measure radiation dam…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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NIH launches major study to unlock secrets of rare bone diseases
Knowledge-focused Recruiting nowThis study has four objectives: 1) to provide investigators the opportunity to study bone specimens from patients with various skeletal diseases; 2) to treat patients with skeletal diseases at the NIH; 3) to expose NIH trainees to certain skeletal diseases; and 4) to gain more kn…
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Short burst exercise safe for COPD lungs, small study finds
Knowledge-focused CompletedThe aim of the study is to observe the ventilatory and cardiac function (included the pulmonary arterial pressure) during an intermittent work exercise test with high density work load.
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Researchers launch registry to track rare endocrine tumors
Knowledge-focused OngoingObjectives: To contribute new and prospective data to our existing database library for patients with MEN1 and MEN2 at The University of Texas M.D. Anderson Cancer Center.
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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10,000 breast cancer patients donate tissue for science
Knowledge-focused Recruiting nowRATIONALE: Collecting and storing samples of tumor tissue from patients with breast cancer to study in the laboratory may help doctors learn more about cancer. PURPOSE: This phase I study is collecting tissue samples for future research from women undergoing surgery for breast c…
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Massive data hunt aims to unlock secrets of stem cell transplants
Knowledge-focused Recruiting nowTo provide the IRB approved mechanism for the prospective collection and analysis on participants who are undergoing either an autologous or allogeneic hematopoietic stem cell transplant for a disease in which a research question is not being addressed.
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Massive NIMH study seeks 16,000 volunteers to unlock secrets of mood and anxiety
Knowledge-focused Recruiting nowThe purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols in the Experimental Therapeutics and Pathophysiology Lab (ETPB) at the National Institute of Mental Health (NIMH) and for the collection o…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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German eye registry reveals shifting trends in corneal transplants
Knowledge-focused Recruiting nowAim of this study is to reflect on the changing trends in absolute numbers, surgical techniques and indications of corneal transplantations being performed in Germany. The Section Cornea of the German Ophthalmological Society provides interim-assessments on a regular basis about…
Sponsor: Universität des Saarlandes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Scientists seek tissue samples to unlock HIV and cancer mysteries
Knowledge-focused Recruiting nowBACKGROUND: * A number of important scientific advances can be made through the study of blood, bone marrow, tumor, or other tissue samples from patients with HIV infection, infection with Kaposi s sarcoma associated herpesvirus (KSHV), infection with other oncogenic viruses, or…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 09, 2026 18:10 UTC
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Big data reveals shifting patterns in rare cancer diagnosis
Knowledge-focused CompletedStage migration occurs when patients sound to have better survival or increased incidence rates at the early stage at diagnosis due to early detection of the disease. As carcinoid tumors are rare and there are no data supporting stage migration, the aim of this study was to perfo…
Sponsor: Suez Canal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Scientists use powerful MRI to map the healthy brain
Knowledge-focused Recruiting nowThe purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnostic tool that provides information about brain chemistry and physiology. This study will evaluate new MRI methods for mon…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Cancer tissue bank aims to fuel future discoveries
Knowledge-focused OngoingDoctors at Memorial Sloan Kettering Cancer Center and at other institutions study normal and cancer cells. To study these cells we need to have human tissue, body fluids, and blood. The patient will be having or have had a procedure to remove tissue. The doctors would like to use…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Brain scans reveal hidden differences in schizophrenia
Knowledge-focused CompletedThe purpose of this study is to use brain imaging technology to compare differences in brain structure, chemistry, and functioning in individuals with brain and mental disorders compared to healthy volunteers. Schizophrenia is a brain disorder that results from subtle changes an…
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Scientists launch massive amyloid sample collection
Knowledge-focused Recruiting nowRATIONALE: Collecting and storing samples of blood, urine, tissue and data from patients with amyloid diseases to test in the laboratory may help the study of this disease in the future. PURPOSE: This research study is collecting samples from patients with amyloid diseases
Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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CLL study seeks 2,750 volunteers to unlock leukemia secrets
Knowledge-focused Recruiting nowThe purpose of this study is to collect human Chronic Lymphocytic Leukemia tissue samples and medical information, in order to find out more about the causes and biology of chronic lymphocytic leukemia.
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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NCI opens screening study for experimental cell therapies in multiple cancers
Knowledge-focused Recruiting nowBackground: The National Cancer Institute Surgery Branch (NCI-SB) has developed experimental therapies that involve taking white blood cells from patients' tumor or from their blood, growing them in the laboratory in large numbers, and then giving the cells back to the patient. …
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 09, 2026 18:10 UTC