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116076 trials found · Page 5614 of 5804
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Packing or not? study questions routine abscess care
Knowledge-focused Recruiting nowThe goal of this study is to examine patients undergoing incision and drainage of cutaneous abscesses to determine if routine packing of the abscess cavity affects the need for further interventions such as repeat incision and drainage, antibiotic administration or hospital admis…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:15 UTC
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Massive breast cancer registry launches to map Real-World patient outcomes
Knowledge-focused Recruiting nowThis study is a prospective, multicenter non-interventional cohort study designed to develop a registry in unresectable locally advanced or metastatic disease.
Sponsor: Spanish Breast Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Healthy volunteer study aims to unlock secrets of aging and blood cell stress
Knowledge-focused CompletedOxidative stress is defined by an excess of reactive oxygen species (reactive oxygen species or ROS) in cells. ROS are essential to cell life (proliferation, differentiation), including kinase activity via inhibition of phosphatases. Very low levels of ROS are observed in quiesce…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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NIH launches massive pain study to unravel mysteries of discomfort
Knowledge-focused Recruiting nowBackground: Researchers want to better understand pain by studying people with and without different kinds of pain. To do this, researchers will expose people to pleasant and unpleasant sensations. They will ask them questions about their pain. Researchers also want to see if th…
Sponsor: National Center for Complementary and Integrative Health (NCCIH) • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Spinach smoothie study reveals immune cell energy secrets
Knowledge-focused OngoingThe purpose of this study is to evaluate mitochondrial function in white blood cells and platelets from healthy individuals following dietary oxalate intake.
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Scientists launch major study to unravel hormone disorders
Knowledge-focused Recruiting nowBackground: There are many endocrine and metabolic-related conditions. Two well-known disorders include diabetes and thyroid disease. Some of these diseases are caused by a change in genes. Researchers want to identify the genes involved in these disorders. They hope this will h…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Tiny brains, big insights: how premature infants' brain waves reveal early development
Knowledge-focused CompletedTemporal theta slow-wave activity (TTA-SW) in premature infants is a specific signature of the early development of temporal networks, as it is observed at the turning point between non-sensory driven spontaneous local processing and cortical network functioning. The role in deve…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists launch tissue collection to unlock lymphoma mysteries
Knowledge-focused Recruiting nowThis document is a protocol for a non-interventional human research study in which the investigator hopes to better understand the changes that take place in T cells in Cutaneous T-cell lymphoma (CTCL). The purpose of this study is to establish a protocol for the collection and s…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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What do patients and doctors really think about acupuncture?
Knowledge-focused OngoingThe proposed qualitative inquiry seeks to understand medical acupuncture from both the physician and the patient perspective. Interviewees will be asked to describe their experiences from the point of diagnosis or training up until the present day to capture the nature of their e…
Sponsor: Mike O'Callaghan Military Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Who speaks for you in the ICU? study reveals gaps in how contact persons are chosen
Knowledge-focused CompletedIn the vast majority of cases, the person of trust (or contact person) is not designated by the patient (emergency, severe disease situations, coma, sedation, etc.). The healthcare team thus identifies a person who 1) may not be the person the patient would have designated and 2)…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Scientists probe how aging skin cells respond to wounds
Knowledge-focused CompletedBackground: Cellular senescence is the aging of cells. It is a complex process that may be connected with aging and age-related diseases. It is unknown if these cells appear around wound sites in humans a few days after skin injury and if there are differences in young and old i…
Sponsor: National Institute on Aging (NIA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Healthy volunteers needed to test new brain scans for addiction research
Knowledge-focused Recruiting nowBackground: Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function. Researchers want to learn more about brain function by using magnetic resonance imaging (MRI). This uses a magnetic field and radio waves …
Phase: NA • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Rocking chair research aims to uncover secrets of balance
Knowledge-focused CompletedFalls in the elderly population are a major public health problem because of their frequency and their consequences, notably in terms of dependence their cost to society. In most cases, balance disorders related to an impaired vestibular system are blamed, even though there is no…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Scientists measure healthy diaphragms to set new standard
Knowledge-focused CompletedThis study is investigating the normal range of maximal diaphragm thickness during a sniff inspiratory manoeuvre using ultrasound in healthy subjects stratified by age and gender.
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Skip the stitches? wisdom tooth study tests Pain-Free recovery
Symptom relief CompletedThe main objective of this study is to evaluate postoperative pain (measured by visual analogue scale (VAS) on day 2 post surgery) in patients operated for avulsion of four wisdom teeth under general anesthesia and for whom the resulting alveoli were NOT sutured versus a similar …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Autism study probes how adults see themselves
Knowledge-focused CompletedThe research aims at clarifying the impact of autism on personal identity in adulthood. Two studies will be made in order to compare adults with autistic spectrum disorders without intellectual deficiency and controls. In the first study (Study A), the investigators will ask subj…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Researchers track severe pneumonia in ICU to improve care
Knowledge-focused Recruiting nowFrom 2003 when Severe Acute Respiratory Syndromes (SARS) appeared,many new types of respiratory viruses emerge in endlessly. Therefore, the epidemiology and the clinical character has changed quietly, especially severe pneumonia. This cohort study aim to obtain the contents of se…
Sponsor: Beijing Chao Yang Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Micro-biopsies may revolutionize skin grafting
Knowledge-focused CompletedThe investigators are doing this research study to learn about how the skin heals after many microscopic skin biopsies are collected. Skin-grafting is a life-saving procedure for people with large area skin wounds caused by burns or trauma. Conventional autologous (self) skin gr…
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Light exposure may sharpen your mind and improve sleep
Knowledge-focused CompletedThe purpose of this project is to study the influence of light on sleep, wakefulness, EEG activity and cognitive performances. The study aim also to evaluate techniques for registration and analysis of the EEG over periods of time.
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Study probes Epinephrine's role in blood vessel health
Knowledge-focused CompletedEpinephrine is the principal physiologic defense against hypoglycemia in type 1 and longer duration type 2 DM. Despite this, it is unknown how epinephrine regulates in-vivo endothelial function and atherothrombotic balance in humans. The specific aim of our study will be to deter…
Phase: EARLY_PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC