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Up to: Hereditary neurological disease · Neurodegenerative disease

Inherited neurodegenerative disorder

An inherited disorder characterized by progressive degeneration and atrophy of the nervous system.

10 trials tagged with this condition →

Frontotemporal dementia 132 trials · 178 incl. sub-types Sub-types →
Hereditary motor neuron disease 1 trial · 169 incl. sub-types Sub-types →
Hereditary cerebellar ataxia 0 trials · 116 incl. sub-types Sub-types →
Huntington disease and related disorders 0 trials · 91 incl. sub-types Sub-types →
Progressive supranuclear palsy 73 trials · 77 incl. sub-types Sub-types →
Leukodystrophy 6 trials · 72 incl. sub-types Sub-types →
Familial Alzheimer disease 13 trials · 55 incl. sub-types Sub-types →
Hereditary spastic paraplegia 27 trials · 33 incl. sub-types Sub-types →
Hereditary optic atrophy 6 trials · 23 incl. sub-types Sub-types →
Neuronal ceroid lipofuscinosis 6 trials · 23 incl. sub-types Sub-types →
Kennedy disease 19 trials
Corticobasal syndrome 19 trials
GM2 gangliosidosis 14 trials · 19 incl. sub-types Sub-types →
Frontotemporal dementia with motor neuron disease 13 trials · 19 incl. sub-types Sub-types →
Posterior cortical atrophy 11 trials
Chediak-Higashi syndrome 9 trials
Neurodegeneration with brain iron accumulation 1 trial · 8 incl. sub-types Sub-types →
Inherited Creutzfeldt-Jakob disease 5 trials
APP-related brain and vascular amyloidosis 0 trials · 5 incl. sub-types Sub-types →
Frontotemporal dementia and/or amyotrophic lateral sclerosis 0 trials · 5 incl. sub-types Sub-types →
TUBB4A-related neurologic disorder 4 trials Sub-types →
Fatal familial insomnia 4 trials
Mitochondrial DNA depletion syndrome 4a 3 trials
Alzheimer disease 17 1 trial
Alzheimer disease 18 1 trial
Ataxia-telangiectasia-like disorder 1 trial Sub-types →
Developmental and epileptic encephalopathy, 35 1 trial
Neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures 1 trial
Neurodegenerative syndrome due to cerebral folate transport deficiency 1 trial
Neuronal intranuclear inclusion disease 1 trial
Recurrent metabolic encephalomyopathic crises-rhabdomyolysis-cardiac arrhythmia-intellectual disability syndrome 1 trial
DCTN1-related neurodegeneration 0 trials Sub-types →
Huntington disease-like 1 0 trials
Huntington disease-like 2 0 trials
ITM2B amyloidosis 0 trials Sub-types →
PEHO syndrome 0 trials
PRKAR1B-related neurodegenerative dementia with intermediate filaments 0 trials
X-linked neurodegenerative syndrome, Bertini type 0 trials
X-linked neurodegenerative syndrome, Hamel type 0 trials
Agenesis of the corpus callosum with peripheral neuropathy 0 trials
Amyotrophic lateral sclerosis-parkinsonism-dementia complex 0 trials
Angioid streaks of choroid 0 trials
Attenuated Chédiak-Higashi syndrome 0 trials
Autosomal recessive cerebral atrophy 0 trials
Boylan dew greco syndrome 0 trials
Cerebellar ataxia-hypogonadism syndrome 0 trials Sub-types →
Cerebral sclerosis similar to Pelizaeus-Merzbacher disease 0 trials
Combined oxidative phosphorylation deficiency 29 0 trials
Deafness dystonia syndrome 0 trials
Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome 0 trials
Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities 0 trials
Early-childhood-onset neurodegeneration with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy 0 trials
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome 0 trials
Encephalopathy due to beta-mercaptolactate-cysteine disulfiduria 0 trials
Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy 0 trials Sub-types →
Facial onset sensory and motor neuronopathy 0 trials
Fatal post-viral neurodegenerative disorder 0 trials
Ferro-cerebro-cutaneous syndrome 0 trials
Hereditary sensory neuropathy-deafness-dementia syndrome 0 trials
Hypotonia, infantile, with psychomotor retardation and characteristic facies 0 trials Sub-types →
Infantile cerebellar-retinal degeneration 0 trials
Infantile-onset axonal motor and sensory neuropathy-optic atrophy-neurodegenerative syndrome 0 trials
Microphthalmia-brain atrophy syndrome 0 trials
Myoclonic cerebellar dyssynergia 0 trials
Neurodegeneration and seizures due to copper transport defect 0 trials
Neurodegeneration with ataxia and late-onset optic atrophy 0 trials
Neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset 0 trials
Neurodegeneration with developmental delay, early respiratory failure, myoclonic seizures, and brain abnormalities 0 trials
Neurodegeneration, childhood-onset, with ataxia, tremor, optic atrophy, and cognitive decline 0 trials
Neurodegeneration, childhood-onset, with cerebellar ataxia and cognitive decline 0 trials
Neurodegeneration, childhood-onset, with cerebellar atrophy 0 trials
Neurodegeneration, childhood-onset, with hypotonia, respiratory insufficiency, and brain imaging abnormalities 0 trials
Neurodegeneration, childhood-onset, with multisystem involvement due to mitochondrial dysfunction 0 trials
Neurodegeneration, childhood-onset, with progressive microcephaly 0 trials
Neurodegeneration, early-onset, with choreoathetoid movements and microcytic anemia 0 trials
Neurodegeneration, infantile-onset, biotin-responsive 0 trials
Neurodegenerative disorder with cerebellar and caudate atrophy 0 trials
Neurodegenerative disorder, X-linked, female-restricted, with parkinsonism and cognitive impairment 0 trials
Psychomotor regression-oculomotor apraxia-movement disorder-nephropathy syndrome 0 trials
Radiation sensitivity/chromosome instability syndrome, autosomal dominant 0 trials
Severe neurodegenerative syndrome with lipodystrophy 0 trials
Striatonigral degeneration 0 trials Sub-types →