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Combined immunodeficiency

A broad classification of inherited disorders presenting at birth that affect both the cell-mediated and humoral aspects of the immune response. Circulating numbers of B lymphocytes, T lymphocytes and NK cells are variable but where present do not function properly. Susceptibility to infection is the primary concern.

3 trials tagged with this condition →

Severe combined immunodeficiency 24 trials · 37 incl. sub-types Sub-types →
Ataxia telangiectasia 11 trials Sub-types →
Wiskott-Aldrich syndrome 10 trials
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia 2 trials
Combined immunodeficiency due to CRAC channel dysfunction 1 trial Sub-types →
Combined immunodeficiency due to ZAP70 deficiency 1 trial
Non-SCID combined immunodeficiency 0 trials · 1 incl. sub-types Sub-types →
IRF4-related combined immunodeficiency 0 trials
MHC class I deficiency 0 trials Sub-types →
NFATC1-related combined immunodeficiency 0 trials
POLD3-related combined immunodeficiency 0 trials
RAC2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome 0 trials Sub-types →
Autosomal dominant combined immunodeficiency due to ERBIN deficiency 0 trials
Autosomal dominant combined immunodeficiency due to partial IL6ST deficiency 0 trials
Autosomal recessive combined immunodeficiency due to IL6R deficiency 0 trials
Autosomal recessive combined immunodeficiency due to complete IL6ST deficiency 0 trials
Autosomal recessive combined immunodeficiency due to partial IL6ST deficiency 0 trials
Combined immunodeficiency due to CD3gamma deficiency 0 trials
Combined immunodeficiency due to CTPS1 deficiency 0 trials
Combined immunodeficiency due to GINS1 deficiency 0 trials
Combined immunodeficiency due to MALT1 deficiency 0 trials
Combined immunodeficiency due to OX40 deficiency 0 trials
Combined immunodeficiency due to POLE2 deficiency 0 trials
Combined immunodeficiency due to RELA haploinsufficiency 0 trials
Combined immunodeficiency due to STK4 deficiency 0 trials
Combined immunodeficiency due to TBX1 deficiency 0 trials
Combined immunodeficiency due to dimerization defective IKAROS mutation 0 trials
Combined immunodeficiency due to moesin deficiency 0 trials
Combined immunodeficiency syndrome 0 trials Sub-types →
Combined immunodeficiency with low Ig due to BCL10 deficiency 0 trials
Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to IKBKA deficiency 0 trials
Early-onset combined immunodeficiency with low ig due to dominant negative IKAROS mutation 0 trials
Late-onset combined immunodeficiency due to ICOSL deficiency 0 trials