Personalized vaccine plus immunotherapy shows promise in lung cancer trial
NCT ID NCT07221474
First seen Nov 01, 2025
Summary
This study tests whether adding a personalized cancer vaccine (V940) to standard immunotherapy (pembrolizumab) and chemotherapy helps people with advanced squamous non-small cell lung cancer live longer and keep their cancer from growing. About 180 adults who have not yet been treated for their metastatic lung cancer will take part. The vaccine is designed to train the immune system to attack each person's unique tumor.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ankara Bilkent Şehir Hastanesi ( Site 1402)
RECRUITINGAnkara, 06800, Turkey (Türkiye)
Contact Phone: •••-•••-••••
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Asan Medical Center ( Site 0503)
RECRUITINGSeoul, 05505, South Korea
Contact Phone: •••-•••-••••
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Bradford Hill Norte ( Site 0308)
RECRUITINGAntofagasta, 1263521, Chile
Contact Phone: •••-•••-••••
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Bradfordhill ( Site 0301)
RECRUITINGSantiago, Region M. de Santiago, 8420383, Chile
Contact Phone: •••-•••-••••
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CHU GABRIEL MONTPIED ( Site 0802)
RECRUITINGClermont-Ferrand, Puy-de-Dome, 63001, France
Contact Phone: •••-•••-••••
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Centre Georges François Leclerc ( Site 0805)
RECRUITINGDijon, Cote-d Or, 21000, France
Contact Phone: •••-•••-••••
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Centro de Estudios Clínicos SAGA ( Site 0307)
RECRUITINGSantiago, Region M. de Santiago, 7500653, Chile
Contact Phone: •••-•••-••••
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Chang Gung Medical Foundation-Linkou Branch ( Site 0605)
RECRUITINGTaoyuan, 33305, Taiwan
Contact Phone: •••-•••-••••
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China Medical University Hospital ( Site 0606)
RECRUITINGTaichung, 404, Taiwan
Contact Phone: •••-•••-••••
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Chungbuk National University Hospital-Internal medicine ( Site 0501)
RECRUITINGCheongju-si, North Chungcheong, 28644, South Korea
Contact Phone: •••-•••-••••
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Cleveland Clinic - Ohio ( Site 0016)
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-••••
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Clinica Adventista Belgrano ( Site 0206)
RECRUITINGCaba., Buenos Aires F.D., C1430EGF, Argentina
Contact Phone: •••-•••-••••
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FALP ( Site 0300)
RECRUITINGSantiago, Region M. de Santiago, 7500921, Chile
Contact Phone: •••-•••-••••
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Fondazione IRCCS Istituto Nazionale Dei Tumori ( Site 1000)
RECRUITINGMilan, 20133, Italy
Contact Phone: •••-•••-••••
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1001)
RECRUITINGRoma, 00168, Italy
Contact Phone: •••-•••-••••
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Fundacion Estudios Clinicos ( Site 0207)
RECRUITINGRosario, Santa Fe Province, S2000DSV, Argentina
Contact Phone: •••-•••-••••
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Hacettepe Universitesi Tıp Fakultesi ( Site 1400)
RECRUITINGAnkara, 06230, Turkey (Türkiye)
Contact Phone: •••-•••-••••
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Hospital Clinico San Carlos... ( Site 1313)
RECRUITINGMadrid, 28040, Spain
Contact Phone: •••-•••-••••
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Hospital Italiano de Buenos Aires ( Site 0200)
RECRUITINGCiudad Autonoma de Buenos Aires., Buenos Aires, C1199ABB, Argentina
Contact Phone: •••-•••-••••
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Hospital Jerez de la Frontera-UGC Oncología ( Site 1315)
RECRUITINGJerez de la Frontera, Cadiz, 11407, Spain
Contact Phone: •••-•••-••••
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Hospital Ramon y Cajal ( Site 1314)
RECRUITINGMadrid, 28034, Spain
Contact Phone: •••-•••-••••
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Hospital Universitari Vall d''Hebron ( Site 1310)
RECRUITINGBarcelona, 08035, Spain
Contact Phone: •••-•••-••••
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Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 1312)
RECRUITINGSeville, 41009, Spain
Contact Phone: •••-•••-••••
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ICO L Hospitalet ( Site 1311)
RECRUITINGHospitalet, Barcelona, 08907, Spain
Contact Phone: •••-•••-••••
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Institut de Cancérologie de l'Ouest ( Site 0801)
RECRUITINGAngers, Pays de la Loire Region, 49055, France
Contact Phone: •••-•••-••••
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Instituto Alexander Fleming ( Site 0201)
RECRUITINGCiudad Autonoma de Buenos Aires, Buenos Aires, C1426ANZ, Argentina
Contact Phone: •••-•••-••••
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Instituto de Investigaciones Clínicas Mar del Plata ( Site 0205)
RECRUITINGMar del Plata, Buenos Aires, B7600FZO, Argentina
Contact Phone: •••-•••-••••
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Koç Üniversitesi Hastanesi ( Site 1403)
RECRUITINGIstanbul, 34010, Turkey (Türkiye)
Contact Phone: •••-•••-••••
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Mackay Memorial Hospital ( Site 0604)
RECRUITINGTaipei, 104, Taiwan
Contact Phone: •••-•••-••••
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Memorial Ankara Hastanesi ( Site 1401)
RECRUITINGAnkara, 06520, Turkey (Türkiye)
Contact Phone: •••-•••-••••
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Moffitt Cancer Center ( Site 0021)
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-••••
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Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 1100)
RECRUITINGWarsaw, Masovian Voivodeship, 02-781, Poland
Contact Phone: •••-•••-••••
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National Cancer Center ( Site 0504)
RECRUITINGGoyang-si, Kyonggi-do, 10408, South Korea
Contact Phone: •••-•••-••••
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National Cheng Kung University Hospital ( Site 0601)
RECRUITINGTainan, 70403, Taiwan
Contact Phone: •••-•••-••••
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National Taiwan University Cancer Center (NTUCC) ( Site 0600)
RECRUITINGTaipei, 106, Taiwan
Contact Phone: •••-•••-••••
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One Clinical Research ( Site 0402)
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact Phone: •••-•••-••••
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Ospedale San Raffaele-Oncologia Medica ( Site 1002)
RECRUITINGMilan, 20132, Italy
Contact Phone: •••-•••-••••
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Ospedale Santa Maria delle Croci-Dipartimento Oncoematologico ( Site 1004)
RECRUITINGRavenna, Emilia-Romagna, 48121, Italy
Contact Phone: •••-•••-••••
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Princess Alexandra Hospital ( Site 0403)
RECRUITINGWoolloongabba, Queensland, 4102, Australia
Contact Phone: •••-•••-••••
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Samsung Medical Center ( Site 0502)
RECRUITINGSeoul, 06351, South Korea
Contact Phone: •••-•••-••••
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Sanatorio Parque ( Site 0203)
RECRUITINGRosario, Santa Fe Province, S2000DSV, Argentina
Contact Phone: •••-•••-••••
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Seoul National University Bundang Hospital ( Site 0500)
RECRUITINGSeongnam-si, Kyonggi-do, 13620, South Korea
Contact Phone: •••-•••-••••
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Taipei Veterans General Hospital ( Site 0602)
RECRUITINGTaipei, 11217, Taiwan
Contact Phone: •••-•••-••••
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Tennessee Oncology, PLLC - Elliston Place Plaza Medical Oncology & Hematology ( Site 9000)
RECRUITINGNashville, Tennessee, 37203, United States
Contact Phone: •••-•••-••••
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Texas Oncology - Central/South Texas ( Site 8002)
RECRUITINGAustin, Texas, 78745, United States
Contact Phone: •••-•••-••••
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Valley Health Systems - Ridgewood Campus ( Site 0010)
RECRUITINGParamus, New Jersey, 07652, United States
Contact Phone: •••-•••-••••
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Virginia Cancer Specialists ( Site 0003)
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-••••
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Washington University School of Medicine ( Site 0024)
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-••••
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Westmead Hospital ( Site 0400)
RECRUITINGWestmead, New South Wales, 2145, Australia
Contact Phone: •••-•••-••••
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Wielkopolskie Centrum Pulmonologii i Torakochirurgii ( Site 1101)
RECRUITINGPoznan, Greater Poland Voivodeship, 60-569, Poland
Contact Phone: •••-•••-••••
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Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1102)
RECRUITINGPrzemyśl, Podkarpackie Voivodeship, 37-700, Poland
Contact Phone: •••-•••-••••
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.