Can fixing reflux fix your esophagus? new study investigates
NCT ID NCT05132816
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether weak esophageal contractions (ineffective motility) improve after partial fundoplication surgery for gastroesophageal reflux. Researchers will perform high-resolution manometry 18-24 months after surgery in 100 patients who had weak contractions before surgery. The goal is to see if the surgery helps restore normal esophageal function.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Spital Limmattal
RECRUITINGSchlieren, Canton of Zurich, 8952, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could show that reflux causes weak esophageal contractions, and that surgery may restore normal function, guiding better treatment decisions.
What could go wrong
This is a small, single-center study with no control group, so results may not apply to all patients. It only measures changes, not whether symptoms improve.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.