New drug duo targets aggressive blood cancer in early trial
NCT ID NCT06863402
First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 24 times
Summary
This study tests a combination of two drugs, nemtabrutinib and pembrolizumab, in 32 people with Richter transformation, a rare and aggressive form of blood cancer that arises from chronic lymphocytic leukemia. The goal is to see if the combination can shrink or eliminate tumors. Participants must have already tried other treatments or be unable to receive standard chemotherapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.