Higher voltage nerve zap may ease chronic migraine
NCT ID NCT07500558
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study tests whether using a higher voltage during a nerve-blocking procedure (pulsed radiofrequency) can better relieve pain in people with chronic migraine who haven't responded to at least two preventive medications. One hundred participants will be randomly assigned to receive either standard or higher-voltage treatment, guided by ultrasound. The main goal is to see if more people get at least 50% pain reduction with the higher voltage.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Minia university
RECRUITINGMinya, 61511, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Minia university raouf
RECRUITINGMinya, 61511, Egypt
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pulsed radiofrequency (standard or higher voltage) applied to the sphenopalatine ganglion
What this could lead to
If it works, this could offer a better, longer-lasting pain relief option for people with chronic migraine who haven't responded to medications.
What could go wrong
This is a small, early-stage trial (100 people) comparing two similar procedures. The higher voltage may not provide extra benefit and could cause discomfort or rare nerve issues.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.