New study reveals hidden fertility risks of modern melanoma drugs

NCT ID NCT07092670

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 23 times

Summary

This study follows 270 women under 40 who have had melanoma removed and are now taking newer drugs (targeted therapy or immunotherapy) to prevent the cancer from coming back. Researchers want to see if these drugs harm the ovaries by measuring a hormone called AMH before and after treatment. The goal is to help doctors and patients decide whether to consider fertility preservation options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Santa Maria della Misericordia - Unità di Oncologia Medica.

    RECRUITING

    Perugia, 06132, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliero-Universitaria, Modena

    NOT_YET_RECRUITING

    Modena, 41125, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    NOT_YET_RECRUITING

    Milan, 20861, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    NOT_YET_RECRUITING

    Roma, 00168, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IOV Istituto Oncologico Veneto

    NOT_YET_RECRUITING

    Padova, 35128, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IRCCS Ospedale Policlinico San Martino, Oncologia Medica 2

    NOT_YET_RECRUITING

    Genova, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Istituto Nazionale Tumori "Fondazione Pascale"

    NOT_YET_RECRUITING

    Naples, 80016, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Oncologico "Giovanni Paolo II"

    NOT_YET_RECRUITING

    Bari, 70122, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Università degli Studi di Siena - U.O.C. Immunoterapia Oncologica Azienda Ospedaliera Universitaria Senese

    NOT_YET_RECRUITING

    Siena, 53035, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Università di Torino - Clinica Dermatologica

    NOT_YET_RECRUITING

    Torino, 10126, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

melanoma skin neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.