Collagen thread boosts lymphedema surgery? stanford trial begins

NCT ID NCT05825157

First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 22 times

Summary

This study tests whether adding a special collagen thread called BioBridge to standard lymph node transfer surgery can better reduce arm swelling in people with lymphedema. About 60 adults with stage I-II arm lymphedema will be followed for 12 months to measure changes in limb volume. The goal is to see if the scaffold helps new lymphatic connections form, improving the surgery's success rate.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LYMPHEDEMA ARM are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford Hospital and Clinics

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BioBridge scaffold (a thread-like collagen device) used alongside standard lymph node transfer surgery

What this could lead to

If it works, this could improve surgical outcomes for people with arm lymphedema, reducing swelling more effectively than surgery alone.

What could go wrong

This is a small, early-stage trial with only 60 people. The device is new, and it may not improve results or could cause complications like infection or scarring.

Conditions

The condition(s) this trial relates to.

lymphedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.