Brain gene therapy hopes to restore dopamine in young Parkinson's patients

NCT ID NCT07267065

First seen Dec 12, 2025 · Last updated May 22, 2026 · Updated 20 times

Summary

This early-stage study tests a gene therapy called AAV2-hAADC in 9 adults aged 18-75 with young onset Parkinson's (symptoms before age 50). The therapy delivers a gene into brain areas that help turn levodopa into dopamine, the chemical missing in Parkinson's. The main goal is to check safety, but researchers will also look for signs of improvement.

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Contacts and locations

Locations

  • The Ohio State University

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.