Will a deeper genetic test unlock better cancer care?

NCT ID NCT04614480

First seen Sep 30, 2025 · Last updated Jun 23, 2026 · Updated 34 times

Summary

This study is testing whether a more detailed 'complex' analysis of a patient's tumor DNA can help doctors choose better treatments than a standard 'simple' analysis. About 8,000 adults with advanced solid tumors will have their exome (genetic code) analyzed both ways. The goal is to see if the complex analysis leads to treatments that would not have been considered otherwise.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CGFL

    RECRUITING

    Dijon, 21079, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU Jean Minjoz

    RECRUITING

    Besançon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Amiens Picardie

    NOT_YET_RECRUITING

    Amiens, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU François Mitterrand

    RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Nantes

    TERMINATED

    Nantes, France

  • Centre Eugène Marquis

    RECRUITING

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Henri Baclesse

    RECRUITING

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Oscar Lambret

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chu Poitiers

    TERMINATED

    Poitiers, France

  • Institut Bergonie

    TERMINATED

    Bordeaux, France

  • Institut Hospitalier Franco-Britannique

    TERMINATED

    Levallois-Perret, France

  • Institut JeanGodinot

    RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exome analysis (genetic test)

What this could lead to

If successful, this could show that a more detailed genetic test helps doctors choose better cancer treatments for patients.

What could go wrong

This is a Phase 2 study, so it is still early. The complex analysis may not lead to better treatment decisions or outcomes for most patients.

Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.