New combo therapy aims to wipe out hidden leukemia cells

NCT ID NCT07108998

First seen Jan 07, 2026 · Last updated Jun 09, 2026 · Updated 24 times

Summary

This study tests whether adding the drug epcoritamab after standard treatment can make chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) disappear more completely. About 22 adults who have already received at least 12 months of a BTK inhibitor (acalabrutinib or zanubrutinib) with or without obinutuzumab will receive epcoritamab for 12 cycles. The goal is to see if this approach leads to undetectable minimal residual disease, meaning no cancer cells can be found in the blood.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC LYMPHOCYTIC LEUKEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.