CLL study tracks genetic shifts during venetoclax therapy

NCT ID NCT03986034

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 34 times

Summary

This study looks at how chronic lymphocytic leukemia (CLL) cells change genetically while patients take the drug venetoclax. Researchers want to understand why some patients respond better than others. About 75 adults with CLL that has come back or not responded to prior treatment will take part. Participants receive venetoclax and have regular blood tests, CT scans, and bone marrow biopsies to track the disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC LYMPHOCYTIC LEUKEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.