New hope for Tough-to-Treat blood cancer: DZD8586 trial opens

NCT ID NCT06539182

First seen Jan 03, 2026

Summary

This study tests a new drug called DZD8586 in 155 adults whose chronic lymphocytic leukemia or small lymphocytic lymphoma has returned or stopped responding to previous treatments. The goal is to see how well the drug shrinks tumors and what side effects it may cause. Participants take the drug alone, and researchers will also measure how much drug stays in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital

    RECRUITING

    Nanjing, Jiangsu, China

  • Research Site

    RECRUITING

    Hefei, Anhui, China

  • Research Site

    RECRUITING

    Beijing, Beijing Municipality, 100053, China

  • Research Site

    RECRUITING

    Beijing, Beijing Municipality, 100191, China

  • Research Site

    RECRUITING

    Guangzhou, Guandong, 510280, China

  • Research Site

    RECRUITING

    Guangzhou, Guandong, 510515, China

  • Research Site

    RECRUITING

    Zhengzhou, Henan, China

  • Research Site

    RECRUITING

    Wuhan, Hubei, China

  • Research Site

    RECRUITING

    Changchun, Jilin, China

  • Research Site

    NOT_YET_RECRUITING

    Dalian, Liaoning, China

  • Research Site

    RECRUITING

    Shenyang, Liaoning, China

  • Research Site

    RECRUITING

    Jinan, Shandong, China

  • Research Site

    RECRUITING

    Linyi, Shandong, China

  • Research Site

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • Research Site

    RECRUITING

    Taiyuan, Shangxi, China

  • Research Site

    RECRUITING

    Tianjin, Tianjin Municipality, 300020, China

  • Research Site

    RECRUITING

    Tianjin, Tianjin Municipality, 300060, China

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia chronic lymphocytic leukemia/small lymphocytic lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.