Real-World study reveals how doctors treat tough colorectal cancer

NCT ID NCT04317599

First seen Jan 08, 2026 · Last updated Jun 02, 2026 · Updated 20 times

Summary

This study looked back at medical records of 274 patients in Europe with a specific genetic mutation (BRAF V600E) in advanced colorectal cancer that had spread. The goal was to see what treatments doctors actually used and how well they worked in everyday practice, not in a controlled trial. The findings help put new experimental treatments into context and may guide future care decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AUSL-IRCCS of Reggio Emilia-Clinical Cancer Center

    Reggio Emilia, Italy

  • AZ Klina

    Brasschaat, Belgium

  • Asst Valle Olona

    Saronno, Italy

  • Azienda Ospedaliero-Universitaria Pisana

    Pisa, Italy

  • Barmherzige Brüder Krankenhaus St. Veit/Glan.

    Saint Veit/Glan, Austria

  • CHC MontLégia

    Liège, Belgium

  • CHRU de Besançon

    Besançon, France

  • CHU Grenoble Alpes

    La Tronche, France

  • CHU de Poitiers

    Poitiers, France

  • Centre Oscar Lambert

    Lille, France

  • Clinica Oncologica Ospedali Riuniti di Ancona

    Ancona, Italy

  • Facharztzentrum Eppendorf

    Hamburg, Germany

  • GHPSO (Groupe Hospitalier Sud de l'Oise)

    Creil, France

  • Gustave Roussy

    Villejuif, France

  • Harrogate & District NHS Foundation Trust

    Harrogate, United Kingdom

  • Hospital General Universitario de Valencia

    Valencia, Spain

  • Hospital del Mar

    Barcelona, Spain

  • Hôpital Franco-Britannique

    Levallois-Perret, France

  • ICM Val d'Aurelle

    Montpellier, France

  • Imelda VZW

    Bonheiden, Belgium

  • Imperial College Healthcare NHS Trust

    London, United Kingdom

  • Instituto Nazionale Tumori, IRCCS, Fondazione G. Pascale

    Naples, Italy

  • Klinikum Aschaffenburg Medical Klinik IV

    Aschaffenburg, Germany

  • La Paz University Hospital

    Madrid, Spain

  • MVZ Mitte Leipzig

    Leipzig, Germany

  • MZ Onkologie Velbert/Ratingen/Mettmann

    Velbert, Germany

  • Medizinische Universität Wien

    Vienna, Austria

  • Oncoresearch Lerchenfeld

    Hamburg, Germany

  • Santa Maria Goretti Hospital

    Latina, Italy

  • Studienzentrale Gokos

    Dresden, Germany

  • UZ Leuven

    Leuven, Belgium

  • University College London Hospitals NHS Foundation Trust

    London, United Kingdom

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham, United Kingdom

  • Universitätsklinikum Essen

    Essen, Germany

Conditions

Explore the condition pages connected to this study.