New hope for leukemia patients who Can't tolerate standard treatment

NCT ID NCT02717611

First seen Jan 08, 2026 · Last updated Jun 18, 2026 · Updated 24 times

Summary

This study tests a drug called ACP-196 (acalabrutinib) in 60 adults with chronic lymphocytic leukemia (CLL) whose cancer returned or didn't respond to treatment and who had to stop ibrutinib because of side effects. The main goal is to see how many patients have their tumors shrink or disappear. Participants take the drug by mouth, and researchers track how long the benefits last and any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Tucson, Arizona, 85704, United States

  • Research Site

    Concord, California, 94520, United States

  • Research Site

    La Jolla, California, 92093, United States

  • Research Site

    Palo Alto, California, 94304, United States

  • Research Site

    Washington D.C., District of Columbia, 20007, United States

  • Research Site

    Chicago, Illinois, 60611, United States

  • Research Site

    Lake Success, New York, 11042, United States

  • Research Site

    New York, New York, 10021, United States

  • Research Site

    Columbus, Ohio, 43210, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Sherman, Texas, USA, United States

  • Research Site

    Seattle, Washington, 98108, United States

  • Research Site

    Seattle, Washington, 98122, United States

  • Research Site

    Spokane, Washington, 99208, United States

  • Research Site

    Milwaukee, Wisconsin, 53226, United States

  • Research Site

    Bruges, 8000, Belgium

  • Research Site

    Bordeaux, 33076, FR, France

  • Research Site

    Haifa, 31000, Israel

  • Research Site

    Madrid, 28006, Spain

  • Research Site

    Bournemouth, BH7 7DW, United Kingdom

  • Research Site

    Leeds, LS9 7TF, United Kingdom

  • Research Site

    Manchester, M20 4BX, United Kingdom

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.