Metal-Free dental implants put to the test against titanium
NCT ID NCT05369299
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether two-piece zirconia dental implants work as well as standard titanium implants when placed right after a tooth is pulled. Thirty-three adults with good oral health received either a zirconia or titanium implant. Researchers measured implant stability and bone loss over time to see if the ceramic option is a reliable metal-free alternative.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dental implant (zirconia or titanium)
- What this could lead to
- If successful, this could show that zirconia implants are a reliable alternative to titanium for immediate tooth replacement, offering a metal-free option.
- What could go wrong
- This is a small, completed trial with only 33 participants, so results may not apply to everyone. Zirconia implants may be more brittle or have different long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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33 people
The number who actually took part.
- Started
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May 2022
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients giving informed consent to participate in the clinical trial and fulfil the following criteria will be included in the investigation: 1. good oral hygiene standard; 2. good general health; 3. 18 years or older; 4. non-smokers; 5. presence of single-tooth or multiple gaps in the mandible or the maxilla; 6. intact facial bone wall; 7. sufficient bone volume to support an implant of at least 10 mm length. 8. Teeth with removable periapical lesions are included. Exclusion Criteria: Primary exclusion criteria are as follows: 1. parafunctional habits; 2. active periodontitis; 3. smoking; 4. pregnancy; 5. acute or chronic medical conditions for which implant therapy has always been considered a contraindication: uncontrolled diabetes (HbA1c \>8.0%), mucosal disease, untreated periodontitis, immunological disorders, active malignancy, alcoholism, condition after radiation therapy to the head and neck area and antiresorptive therapy. Secondary exclusion criteria will be applied at surgical procedure: 6. loss of facial bone wall due to extraction procedure; 7. insufficient primary stability (less than 32Ncm insertion torque).
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Private practice Prof. Polansky
Graz, Styria, 8010, Austria