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Promising combo for tough breast cancer tested, but trial stopped early

NCT ID NCT03901469

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 32 times

Summary

This study tested a combination of two drugs, ZEN003694 and talazoparib, in people with triple-negative breast cancer who do not have BRCA gene mutations. The goal was to see if the combo could shrink tumors or slow the disease. The trial was stopped early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Affliated Hospital of Jining Medical University

    Jining, Shandong, 272000, China

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Emory University Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Hunan Cancer Hospital

    Changsha, Hunan, 410000, China

  • Institut Jules Bordet

    Anderlecht, 1070, Belgium

  • MD Anderson

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • START Madrid

    Madrid, 28050, Spain

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510289, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • Tennessee Oncology (Sarah Cannon)

    Nashville, Tennessee, 37203, United States

  • The First Affiliated Hosptial of Bengbu Medical College

    Bengbu, Anhui, 233000, China

  • The Second People's Hospital of Neijiang

    Neijiang, Sichuan, 641100, China

  • Tianjing Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • UZ Leuven

    Leuven, 3000, Belgium

  • University of Kansas Cancer Center

    Westwood, Kansas, 66203, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Vall d'Hebron Institute of Oncology (VHIO)

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.