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New drug targets rare lung cancer gene in phase 2 trial

NCT ID NCT06933329

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 31 times

Summary

This study tests an experimental drug, zelenectide pevedotin, in people with advanced non-small cell lung cancer that has a specific genetic change called NECTIN4 amplification. Participants must have already tried at least one prior cancer treatment. The goal is to see if the drug can shrink tumors and to check its safety. About 73 adults will take part across two groups based on lung cancer subtype.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Complejo Hospitalario Universitario A Coruña

    A Coruña, 15006, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Institut Curie

    Paris, 75005, France

Conditions

Explore the condition pages connected to this study.