New combo therapy for lymphoma shows promise in early trial
NCT ID NCT04850495
First seen Nov 24, 2025 · Last updated Apr 29, 2026 · Updated 19 times
Summary
This early-stage trial tests a new drug, zanubrutinib, added to a standard chemotherapy cocktail (R-PolaCHP) for people newly diagnosed with diffuse large B-cell lymphoma. The main goal is to find the safest dose and watch for side effects. About 38 adults with this type of lymphoma will take part.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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MUSC
Charleston, South Carolina, 29425, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
Conditions
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