New eczema ointment shows promise in early trial
NCT ID NCT06309355
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new ointment called YR001 in 35 adults with mild to moderate atopic dermatitis (eczema). The main goal was to check if the ointment is safe and how the body processes it. Researchers also looked at whether it improves skin condition. The trial was completed and placebo-controlled.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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35 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Nov 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Written informed consent obtained from the subject. 2. Male or female subject is aged 18 or older. 3. Subject has a weight of at least 50 kg and a body mass index (BMI) between 18.0 and 30.0 kg/m2, inclusive. 4. An Investigator Static Global Assessment (ISGA) score of 2 (mild) to 3 (moderate) at screening and Baseline. Exclusion Criteria: 1. Pregnant or lactating women. 2. Any skin tattoo, scar, cuts, bruises, or other skin damage, including excessive UV exposure, at the possible IP application sites. 3. Patients who have a source of itch solely or significantly from untreatable areas (face, scalp, genitals, palms of hands or soles of feet). 4. Have concomitant skin disease or infection (e.g., acne, impetigo) or presence of skin comorbidities in the skin areas to be dosed that may interfere with study assessments and treatment response. 5. Participation in another interventional clinical trial (e.g. investigational drug, biological agent, or device) within 30 days or 5 half-lives of investigational agent (whichever is longer) before entering, or during the trial, or previous participation in this clinical trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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DelRicht Research
Baton Rouge, Louisiana, 70809, United States
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Encore Medical Research -Boynton Beach
Boynton Beach, Florida, 33436, United States
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Encore Medical Research-Hollywood
Hollywood, Florida, 33331, United States
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Encore Medical Research-Weston
Weston, Florida, 33331, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Is your nose fueling infected eczema and scabies sores?
- Can an eczema drug reshape the Skin's microbial community?