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Can a daily serum regrow thinning hair? small study aims to find out

NCT ID NCT07228156

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether a daily plant-based serum can safely improve hair growth in 40 men and women with mild to moderate thinning hair. Participants apply the serum to their scalp for 9 months, and researchers measure changes in hair density and thickness using special cameras. The goal is to see if the serum is effective and satisfying to use, while monitoring for any side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Xtresse serum (plant-based extract blend)
What this could lead to
If it works, this could point toward a non-prescription serum to improve hair density and thickness in people with mild to moderate thinning hair.
What could go wrong
This is a small pilot study with only 40 participants and no control group. Results may not apply to everyone, and the serum may not work better than existing products.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women and Men Aged 18-65 years with self-perceived hair thinning (confirmed by an investigator). * Fitzpatrick skin Types I to IV * Ludwig Scale I or II or Norwood Scale 1 to 4 (mild to moderate thinning hair) * Agree to maintain their current diet, medication, exercise routines, hair shampooing, and color treatment frequency for the duration of the study. * Ability and willingness to comply with the study protocol including regular visits and product application. * Written informed consent obtained, including written consent to allow photographs to be used as part of the study data and documentation. * For females of childbearing potential, a negative pregnancy test at screening. * Commitment to using effective contraception throughout the study. Exclusion Criteria: * Pregnancy, nursing, planning to become pregnant. * Initiation of hormone therapy or changes in hormonal therapy within 6 months prior to enrollment and throughout the study. * Use of other medical hair loss treatments (e.g. Minoxidil, Dutasteride, Finasteride, laser or light therapy) within 3 months prior to the study and throughout the study. * Microneedling, PRP, or other physical treatment modality on the scalp within 6 months prior to the study and throughout the study. * Use of GLP-1 inhibitors (e.g. semaglutide) within 6 months prior to the study and throughout the study. * Known uncontrolled health conditions (poorly controlled diabetes, hypertension). * History of scalp disorders that could interfere with study results. * Known sensitivity to any of the ingredients in the study medication. * In the investigator's opinion, evidence of unwillingness, or inability to follow the restrictions and requirements of the protocol and complete the study. * Subject has any conditions, findings in history, physical exam, or laboratory assessments, which in the opinion of the investigator, would exclude the subject from continuing in this study. * Treatment with an experimental drug, biologic, or device within 12 weeks of the screening visit.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Dermatology & Cosmetic Surgery

    Maitland, Florida, 32751, United States

  • Kindred Hair and Skin Center

    Marriottsville, Maryland, 21104, United States

  • Root Hair Institute

    Bellevue, Washington, 98004, United States

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