Herbal capsule tested to fight chemo exhaustion in blood cancer survivors
NCT ID NCT07084662
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether Xinlikang capsules can reduce severe fatigue and improve immune health in people with diffuse large B-cell lymphoma who have finished chemotherapy and are in remission. About 80 participants will receive either the capsule or a placebo. The goal is to see if this treatment can ease lingering tiredness and help the body recover after cancer therapy.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Aug 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥18 years old; 2. Newly diagnosed diffuse large B lymphoma (DLBCL); 3. Patients had completed the first-line treatment of chemotherapy and immunotherapy and the course of treatment had been completed. 4. Metabolic complete response (CR) was evaluated by PET/CT during or after chemotherapy. 5. Had completed the full course of chemotherapy-containing regimen for more than 30-90 days; 6. BFI fatigue score ≥4; 7. The expected survival time was ≥6 months; 8. No treatment plan for CD20 monoclonal antibody, radiotherapy, chemotherapy, lenalidomide, thymopeptides, targeted drugs, biological agents, immunosuppressive agents, other Chinese medicine decoction or Chinese patent medicine in the next 3 months; 9. No grade 3-4 surgery plan is expected in the next 3 months; 10. They had normal mental consciousness, could understand the content of the questionnaire correctly, and could complete the questionnaire with assistance or independently; 11. Women and men of childbearing age agreed to use contraception during and for 1 month after treatment; 12. They volunteered to participate in the clinical trial and signed the informed consent form, which was in accordance with the requirements of Good Clinical Practice (GCP). Exclusion Criteria: 1. DLBCL subjects with CNS involvement at initial diagnosis; 2. Allergic or intolerant to Xinlikang capsule or its component drugs; 3. Significant abnormal liver and kidney function: ALT, AST, GGT≥3 ULN; BUN and Cr≥3 ULN; 4. Severe abnormal bone marrow function: white blood cell ≤1.0×10\^9/L, neutrophil ≤0.5×10\^9/L, platelet ≤30×10\^9/L, hemoglobin ≤6g/dL; 5. Patients with HIV virus infection, bacterial infection and other immune-related diseases that affect immune function as judged by clinicians; 6. Uncontrolled HBV or HCV infection: Hepatitis B Virus (HBV) DNA testing exceeding the lower limit of detection or 1000 copies /mL or 500 IU/mL (the higher is the reference) during screening in patients with a history of chronic hepatitis B; HCV RNA detection in patients with a history of Hepatitis C Virus (HCV) infection during the screening period exceeded the detection limit of the assay or 1000 copies /mL or 500 IU/mL (whichever was higher was used as a reference). 7. Patients with other malignancies. 8. Enrollment in another clinical trial 30 days before screening or during the trial; 9. Persons who were deemed by the investigator to be ineligible to participate in the trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University
RECRUITINGGuangzhou, Guangdong, 510060, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Proton beams vs. X-Rays: can a pricier radiation spare hearts and prevent second cancers?
- Can 'Memory-Enhanced' immune cells outsmart lymphoma?
- Can a Two-Drug combo keep aggressive lymphoma at bay?
- Can a 'Universal' cancer target outsmart resistant blood cancers?
- Can a single shot build a cancer army inside the body?
- Can a smart immune cell with a kill switch beat tough lymphomas?