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Experimental cancer drug WTX212A enters first human tests

NCT ID NCT07269899

First seen Dec 08, 2025 · Last updated Jun 23, 2026 · Updated 28 times

Summary

This early-phase study is testing an experimental drug called WTX212A, given alone or after radiation therapy, in 12 people with advanced solid tumors. The main goal is to see if the drug is safe and whether it can shrink tumors. Because this is a phase 1 trial, it is very small and focused on safety, not proof of a cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Center of SUN YAT-senU

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cancer center of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510060, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

WTX212A (erythrocyte-αPD-1 antibody conjugate) and radiotherapy

What this could lead to

If it works, this could point toward a new treatment option for advanced solid tumors that are hard to treat.

What could go wrong

This is a very early phase 1 trial with only 12 participants, so it is too small to prove effectiveness. The treatment may not shrink tumors or could cause side effects.

Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.