Could a simple wrist injection silence arthritis pain?
NCT ID NCT07814989
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
Researchers are testing whether a wrist nerve block, which uses a local steroid injection to interrupt pain signals, can reduce wrist pain in adults with rheumatoid arthritis. The trial enrolls 180 people with oligoarticular rheumatoid arthritis that affects the wrist. Participants receive the injection, and researchers track changes in pain scores over 16 weeks to see if the procedure helps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a wrist nerve block injection using local steroid
- What this could lead to
- If it works, this could offer a less invasive way to relieve wrist pain for people with rheumatoid arthritis, possibly delaying or avoiding surgery.
- What could go wrong
- This is an early study with no control group, so any pain relief could be due to the placebo effect or natural fluctuation. Nerve blocks carry small risks of infection, bleeding, or temporary numbness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. RA patients fulfilled the 2010 American College of Rheumatoid Arthritis classification criteria.\[8\] 2. Oligoarticular RA patients including wrist joint. 3. Age above 18 years old. 4. Patient cooperative and can answer questions. Exclusion Criteria: 1. Other rheumatologic or collagen diseases. 2. Age below 18 years. 3. Patients who underwent concomitant procedures to address underlying pathology such as radial styloidectomy, ulna shortening, fracture fixation, arthroplasty, arthrodesis, and ligament reconstructions. 4. Patients who suffered from hand deformities or limitation. 5. Uncooperative patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sohag University Hospital
Sohag, Egypt
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