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New wound dressing aims to cut infection risk in severe leg breaks

NCT ID NCT06337292

First seen May 17, 2026 · Last updated May 22, 2026 · Updated 1 time

Summary

This study tests whether a special vacuum dressing (negative pressure wound therapy) can reduce infections and other wound problems after surgery for high-risk leg fractures. About 352 adults with severe tibia fractures will be randomly assigned to get either the vacuum dressing or a standard bandage. The goal is to see which approach leads to fewer complications like infections, additional surgeries, or poor wound healing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dartmouth-Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 03756, United States

    Contact

  • Inova Fairfax MEdical Campus

    RECRUITING

    Falls Church, Virginia, 22042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UTHealth/McGovern Medical School

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland R Adams Cowley Shock Trauma Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact

  • University of Maryland Shock Trauma/Capitol Regions

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.