Blueberry powder tested as natural joint pain remedy

NCT ID NCT06828159

Symptom relief Sponsor: University of Nevada, Las Vegas Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether eating freeze-dried wild blueberry powder every day for 12 weeks can improve gut health, reduce inflammation, and ease joint pain in adults with arthritis. Fifty participants will take either the blueberry powder or a placebo, with a 2-week break between treatments. Researchers will measure blood markers of inflammation and joint function, as well as self-reported pain levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: freeze-dried wild blueberry powder
What this could lead to: If it works, this could point toward a simple dietary supplement to help manage joint pain and inflammation.
What could go wrong: This is a small, early-stage trial with only 50 participants, so results may not apply broadly. The effect may be modest or no better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults with documented multi-joint/knee arthritis Exclusion Criteria: * inability to give informed consent * pregnancy or lactation * planned knee replacement surgery * allergy or contraindication to berries * recent trauma of the knee responsible of the symptomatic knee * intra-articular injection in the target knee/hip in the last 3 months * oral corticosteroid therapy ≥ 5 mg/day (prednisone equivalent) at baseline * use of berry extracts in the last 3 months * special diets * cancer treatment * bone diseases

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Conditions

The condition(s) this trial relates to.

Arthralgia arthritic joint disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gut microbiota Inflammation biomarkers Joint pain Pain assessment

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Blueberry powder tested as natural joint pain remedy

What the study statuses mean