Smartphone-Guided weight loss trial aims to boost heart health in obese patients
NCT ID NCT07514611
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a personalized diet and exercise program guided by a smartphone app in 140 obese adults with coronary heart disease. Participants receive custom meal plans and daily weight tracking to help them lose weight safely. The goal is to see if this approach improves weight, body fat, and overall heart health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- personalized diet and exercise program
- What this could lead to
- If successful, this could provide an effective, scalable weight-loss method to improve heart health and metabolic outcomes in obese patients with coronary heart disease.
- What could go wrong
- This is a small, early-stage trial (140 participants) testing a behavioral intervention, so results may not apply broadly. Weight loss can be difficult to sustain, and the software's guidance may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 140 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age range: 18-65 years old . 2. History of coronary heart disease confirmed by coronary angiography or coronary CTA, showing ≥50% stenosis in at least one major coronary artery (left main coronary artery, left anterior descending artery, left circumflex artery, right coronary artery); or a definite history of myocardial infarction, or prior coronary revascularization (PCI or CABG). 3. BMI: Body Mass Index (BMI) ≥ 28 kg/m² 4. Weight loss willingness: Has the intention to lose weight 5. Smartphone proficiency: Able to use a smartphone. 6. Daily living ability: Capable of performing basic activities of daily living independently. 7. Informed consent: Voluntarily participates in the study, signs a written informed consent form, and is willing to cooperate with follow-up Exclusion Criteria: 1. Unstable angina pectoris or acute myocardial infarction occurring within the previous month; 2. Comorbid endocrine or neurological diseases, cancer, or a history of bariatric surgery that affect body weight; or long-term use of medications that impact body weight; 3. Comorbid diseases that affect exercise capacity, such as severe cardiopulmonary diseases or osteoarthritic conditions; 4. Comorbid diseases that affect diet, such as severe mental disorders, bulimia or anorexia nervosa, or cognitive dysfunction; 5. Significant liver or kidney dysfunction, defined as: glomerular filtration rate \< 60 ml/(min·1.73m²) or undergoing dialysis; alanine transaminase (ALT) or aspartate transaminase (AST) ≥ 3 times the upper limit of the normal range specified by the research center; 6. Severe language, psychological, or physical disabilities that prevent participation in the protocol; 7. Pregnant or lactating women, or individuals of childbearing potential who are unwilling/unable to use effective contraceptive measures; 8. Participation in other interventional clinical trials; 9. Body weight change exceeding 5% within the past year; 10. Patients with a habit of long-term high-intensity exercise(more than 2 sessions per week of high-intensity endurance training, or more than 3 sessions per week of moderate-intensity endurance training); 11. Patients deemed unsuitable for participation in the study by the researchers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Guangdong Provincial People's Hospital
RECRUITINGGuangzhou, Guangdong, 510080, China
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