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New drug targets tough KRAS cancers in early trial

NCT ID NCT07148128

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 28 times

Summary

This study tests a new drug called WEF-001 in about 110 adults with advanced solid tumors (pancreatic, colorectal, lung, ovarian, bile duct, or bladder cancer) that have a KRAS gene mutation and have stopped responding to standard treatments. The goal is to check the drug's safety and see if it can shrink tumors. Participants receive WEF-001 alone, and the study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NEXT Oncology Dallas

    RECRUITING

    Dallas, Texas, 75230, United States

    Contact Email: •••••@•••••

    Contact

  • Next Oncology, San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Email: •••••@•••••

    Contact

  • Oxford University Hospital

    RECRUITING

    Headington, Oxford, 0X3 9DU, United Kingdom

    Contact

    Contact

    Contact

  • Princess Margareth Cancer Center

    RECRUITING

    Toronto, Ontario, Canada

    Contact

Conditions

Explore the condition pages connected to this study.