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Fingertip wrinkle test may spot nerve damage

NCT ID NCT07255573

Diagnosis Sponsor: HOSPITAL BRITANICO DE BUENOS AIRES Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a 15-minute hand soak in warm water can help diagnose small fiber neuropathy, a condition that causes pain, numbness, and problems with automatic body functions. Researchers tested 38 adults and compared the wrinkling pattern of their fingertips to standard nerve tests. The goal was to see if this simple, low-cost method could reliably detect nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

38 people

The number who actually took part.

Started

Nov 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults evaluated at the Neuromuscular Department and Neurophysiology Laboratory of Hospital Británico de Buenos Aires (Argentina), a tertiary referral center. The source population includes consecutive clinic patients referred for assessment of suspected small-fiber neuropathy and healthy adult volunteers recruited from the hospital community. Recruitment occurs during routine outpatient activity; all index/comparator testing is performed on site.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years. * Suspicion of small-fiber neuropathy based on history and/or physical examination by a neuromuscular neurology specialist. * Sensory and motor nerve conduction studies within normal limits. * Prior QST performed, regardless of result. * Prior SSR performed, regardless of result. Exclusion Criteria: * Patients under 18 years. * Individuals who do not wish to participate in the study or who decline informed consent. * Patients with any contraindication to any of the aforementioned studies. * Neurophysiological studies demonstrating large-fiber involvement.

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Conditions

The condition(s) this trial relates to.

autonomic nervous system disorder dysautonomia primary erythermalgia Small Fiber Neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dysautonomia Small fiber neuropathy

Contacts and locations

Locations

  • Hospital Britanico de Buenos Aires

    Buenos Aires, Buenos Aires F.D., 1428, Argentina

More trials for these conditions

Other studies related to the condition(s) this trial covers.