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Does water temperature matter during sedated endoscopy? new study investigates

NCT ID NCT05454475

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 270 adults undergoing sedated ultrasound endoscopy to see if the temperature of water used during the procedure affects image quality, patient comfort, and safety. Participants were randomly assigned to receive cold, warm, or hot water. The goal is to find the optimal temperature that reduces gut movement and improves diagnosis while keeping patients comfortable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
water at different temperatures (cold, warm, hot)
What this could lead to
If successful, this could identify the best water temperature to improve image quality and patient comfort during sedated ultrasound endoscopy.
What could go wrong
This is a completed study focused on a procedural detail, not a new treatment. Results may not change practice if differences are small or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

270 people

The number who actually took part.

Started

Jun 2022

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

In the Third Xiangya Hospital of Central South University, the First Affiliated Hospital of South China University, the South China Hospital Affiliated to the University of South China, the Hunan Provincial People's Hospital, and the First People's Hospital of Changde City, patients with small probe ultrasound endoscopy under intravenous anesthesia due to gastrointestinal bulge lesions.

Ages

18 to 75 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Age ≥ 18 years old; * Gastrointestinal (GI) mucosal or submucosal lesions detected by general endoscopy; * Require small-probe ultrasonic endoscopy (mEUS) under sedation for definitive diagnosis; * Clearly understand the study and voluntarily participate, with informed consent provided. Exclusion Criteria * Failure to meet the requirements for mEUS examination and anaesthesia, or need to use multiple sedative and analgesic drugs; * Pregnancy or breastfeeding; * Chronic use of opioids and benzodiazepines; * Structural changes in the GI tract caused by abdominal surgery; * Presence of mental illness; * Presence of lesions in the oesophagus.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • he Third Xiangya Hospital of Central South University

    Changsha, Hunan, 410013, China