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Water as medicine? study tests its effect on heart transplant patients

NCT ID NCT00581321

Knowledge-focused Sponsor: Satish R. Raj Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests how drinking 500 ml of water affects blood pressure and heart function in 40 stable heart transplant patients. Researchers will measure changes in blood vessel resistance and blood pressure over 40 minutes. The goal is to understand if water can be a simple way to manage blood pressure in this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
water
What this could lead to
If it works, this could help doctors understand how water affects blood pressure in heart transplant patients, potentially guiding future care.
What could go wrong
This is a small, early study with only 40 participants. It only looks at short-term effects and may not apply to all heart transplant patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Jan 2006

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * s/p cardiac transplantation scheduled for clinical right heart catheterization * age \> 18 years Exclusion Criteria: * significant tricuspid regurgitation * inability to safely swallow 500 ml of water * other major medical comorbidities such as advanced renal disease where water ingestion may be harmful to patient

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure Cardiac transplantation

Contacts and locations

Locations

  • Tennessee Valley Health Systems (Nashville VA)

    Nashville, Tennessee, 37212, United States

  • Vanderbilt University

    Nashville, Tennessee, 37232, United States

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