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Eccentric exercise may boost walking in knee osteoarthritis

NCT ID NCT03167502

Symptom relief Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether eccentric muscle training (lengthening exercises) improves walking performance in people with knee osteoarthritis compared to standard concentric training (shortening exercises). Forty adults aged 40-85 with knee osteoarthritis participated in 6 weeks of supervised exercise twice a week. The main goal was to see how far they could walk in 6 minutes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
eccentric muscle training
What this could lead to
If this works, it could point toward a better exercise program to help people with knee osteoarthritis walk farther and with less fatigue.
What could go wrong
This is a small, early study with only 40 participants, so results may not apply to everyone. The intervention is exercise-based, so benefits may be modest and require ongoing effort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Sep 2017

Finished

Jun 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Autonomous subjects aged 40 to 85 * Subjects meeting ACR criteria for gonarthrosis * Subjects with a score of Kellgren and Lawrence at least one knee greater than or equal to 2 * Signature of consent form * Subjects affiliated to social security Exclusion Criteria: Subject with a Kellgren and Lawrence stadium at 4 for at least one of his two knees * Subjects with symptomatic femoro-patellar arthrosis * Subject with a pathology that makes walking testing impossible. * Non-autonomous subjects, with a pathology impairing walking * Subjects with symptomatic osteoarthritis of the hip and / or with a hip or knee prosthesis * Subject incapable of signing consent and unable to understand information leaflet.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis

Contacts and locations

Locations

  • Department of rheumatology, nice university hospital

    Nice, 06000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.