Seaweed as medicine? wakame put to the test against kidney disease
NCT ID NCT07729683
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether eating 5 grams of wakame seaweed daily for three months can lower levels of harmful AGEs in the blood of people with stage III chronic kidney disease. AGEs are compounds that may speed up kidney damage. The study includes 30 adults who will add the seaweed to their meals using recipes from a Michelin-starred chef. The goal is to see if this simple dietary change can offer extra kidney protection on top of standard care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a daily 5-gram dose of wakame (Undaria pinnatifida) seaweed flakes
- What this could lead to
- If it works, this could offer a simple, sustainable dietary addition to help slow the progression of chronic kidney disease.
- What could go wrong
- This is a small, early-stage trial with only 30 participants, so results may not apply broadly. The effect on kidney function is uncertain, and dietary changes can be hard to maintain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients not under legal protection * Patients aged ≥ 18 and \< 90 years * Patients with stage IIIA-B chronic kidney disease (CKD) (estimated GFR by CKD-EPI ≥ 30 mL/min and \< 60 mL/min) * Patients receiving optimized nephroprotective treatment (ACE inhibitors, SGLT2 inhibitors) * Patients who have signed the informed consent form * Patients not participating in another clinical study * Patients affiliated with or benefiting from a social security scheme Exclusion Criteria: * Adult patients under legal protection * Patients under 18 years old or over 90 years old * Patients with uncontrolled thyroid disorders * Patients with decompensated heart failure * Patients consuming other dietary supplements containing seaweed or iodine (e.g., multivitamins) * Pregnant or breastfeeding women * Patients with acute kidney injury * Patients who decline to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Groupe Hospitalier de La Rochelle Ré Aunis
RECRUITINGLa Rochelle, 17000, France
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